Precision medicine’s chicken and egg problem
After 15 years of completing the human genome project, the progress of precision medicine appears to be very slow. Some believe it is due to precision medicine and companion diagnostics have a chicken and egg problem. Drug companies that would be developing a companion diagnostic need to understand the molecular basis of the disease in order to test something. They often have to develop something in parallel using diagnostics development and assay development testing in the entire diagnostics realm of the world. However, they usually hesitate to invest in that before they know they have efficacy or signs of efficacy in the drug being developed. When precision medicine is promising and exciting, to actually move to healthcare delivery, it has to demonstrate scale, which so far it has not yet.